When it comes to Cpanel, Fantastico has been the most popular form of auto installing WordPress. The new software Softaculous has replaced Fantastico providing more software for automatic installation and upgrade.
There are more New features are available including a user-feedback rating system, software demonstrations, and more.
Softaculous currently offers 131 applications and scripts for quick, easy installation. With Softaculous you can able to automatically install WordPress MU.
Softaculous is best as compare to Fantastico but its little confussing for new clients who just registered hosting account. I think Softaculous need some time to undterstand for new clients.